Chemokines in Viral Infections
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Edited By:Surendran MahalingamJohn Curtin School of Medical Research ISBN: 978-0-306-48234-2 Published: 2004-11-01 This book may be purchased as an eBook (pdf) for $99, or individual chapters (pdf) may be purchased from the list below for $19. |
Chapters available from this book
Herpesvirus Encoded Chemokines and Chemokine Receptors
Thomas N. Kledal
Herpesviruses and poxviruses have pirated components of the host chemokine system and optimized these proteins to increase their success during infection. Both the beta-herpesviruses, e.g., human cytomegalovirus (HCMV), and the gamma-herpesviruses, e.g., Kaposi’s sarcoma associated herpesvirus (KS...
The Chemokines: What Are They and What Do They Do?
Shaun R. McColl
Whole body coverage by leukocytes is a critical feature of immunity. Various leukocyte populations flow through the peripheral blood, and depending on whether they encounter appropriate signals, they may move into inflamed tissues to deal with infections as is the case with myeloid cells, or into va...
Soluble Chemokine Binding Proteins Encoded by Viruses
Vincent P. Smith, Neil A. Bryant and Antonio Alcami
Chemokines are chemoattractant cytokines that regulate trafficking and effector functions of leukocytes, and play a key role in inflammation and host defence against invading pathogens.1,2 For a detailed description of the chemokine family see chapter 1. The induction of particular chemok...
Approaches to Viral Vaccine Development Involving Chemokine Receptors and Their Ligands, with Special Reference to Human Immunodeficiency Virus 1
Gordon Ada
There are currently registered vaccines against 22 infectious agents pathogenic for humans and candidate vaccine preparations against 18 other infectious agents have undergone phase II clinical trials.1 Some of these later preparations may become licensed for medical use within the n...
CX3C Chemokine Mimicry by Respiratory Syncytial Virus G Glycoprotein
Ralph A. Tripp
Chemokines are small disulphide-linked polypeptides that act as potent chemoattractants for many cell types including lymphocytes, monocytes, macrophages, neutrophils and NK cells. As described in chapter 1 chemokines are divided into subfamilies based upon cysteine signature motifs termed C, CC,...
A Role for Chemokine Activity in Alphavirus Pathogenesis: Evidence from the Analysis of Polyarthritis and Myalgia Post Ross River Virus Infection
Brett A. Lidbury and Surendran Mahalingam
Ross River virus (RRV) is an \"Old World\" alphavirus of the Semliki Forest group1 and the etiological agent of the most common arthropodborne viral disease in Australia. RRV has a positive strand RNA genome comprising 11,851 nucleotides in a single strand organized into regions encoding ...
Chemokine Expression and Granulocyte Recruitment in Response to Acute Pneumovirus Infection in vivo
Helene F. Rosenburg and Joseph B. Domachowske
The use of appropriate infectious agents in mice to mimic viral infection in man is essential to the understanding of human disease. In this Chapter, we focus on our recent findings on the inflammatory responses to respiratory virus infection using a novel model to study diseases caused by pneumov...
