Chapter category: Protein
The Role of LIGHT in Autoimmunity
TNF Superfamily
Edited by: Sanjay KhareISBN: 978-1-58706-306-0
» Get more information about this book at landesbioscience.com «
Chapter authors:
Jing Wang and Yang-Xin Fu
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Jing Wang
Department of Pathology and Committee on Immunology, University of Chicago
Yang-Xin Fu
Department of Pathology, University of Chicago
Additional chapters from this book:
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Skeletal homeostasis is maintained by a delicate balance between bone-resorbing osteoclasts and bone-building osteoblasts. Recently, three novel tumor necrosis factor (TNF) ligand and receptor...
CD40 and CD154
Iqbal S. Grewal
CD40 is a cell surface receptor that belongs to the tumor necrosis factor (TNF) receptor superfamily and was initially shown to be critical for mediating contact-dependent signals between B an...
The Role of LIGHT in Autoimmunity
Jing Wang and Yang-Xin Fu
This chapter focuses on the role of LIGHT in the induction of auto- immunity. LIGHT and LTab share the same receptor, LTbR, and coop- erate in lymphoid organogenesis and development of lymphoid ...
Regulation of T Cell Immunity by OX40 and OX40L
Michael Croft, Shahram Salek-Ardakani, Jianxun Song, Takanori So and Pratima Bansal-Pakala
OX40 (CD134) and its binding partner OX40-ligand (OX40L) represent members of the TNFR and TNF superfamilies that appear to be crucial to many types of immune reaction mediated by T cells. Eme...
Tumor Necrosis Factor (TNF) and Neurodegeneration
Rammohan V. Rao, H. Michael Ellerby and Dale E. Bredesen
Cytokines are a family of growth factors that are secreted by the cells of the immune system. The family includes interleukins (IL), interferons (IFN), tumor necrosis factors (TNF), chemokines...
CD137 Pathway in Innate and Adaptive Immunity
Ryan A. Wilcox and Lieping Chen
CD137 is a member of the TNF receptor superfamily which may be induced on a variety of cells, including activated T lymphocytes, natural killer cells and dendritic cells. Studies performed bot...
