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Chapter category: Circadian Rhythms

Diverse Outputs Regulated by the Neurospora Circadian Clock

Chapter authors:
Alejandro Correa, Zachary Lewis, Andrew Greene, Michael Vitalini, Louis Morgan, Kyung Suk Seo and Deborah Bell-Pedersen


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A complete understanding of the circadian system requires a detailed description of the genes that are regulated by the clock, along with the mechanisms by which circadian oscillators signal time information to regulate the output pathways. Research in Neurospora crassa pioneered the isolation of clock-controlled genes (ccgs) and has furthered our understanding of how the clock transmits information through the output pathways to regulate rhythmic processes. In this chapter, we will review what is currently known about the output pathways in N. crassa and the possible mechanisms by which the central oscillator controls rhythmic gene expression. In addition, we will compare what is known about the N. crassa circadian clock to that of another ascomycete, Aspergillus.

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