Chapter category: Reproductive Biology
Developmental, Behavioral and Physiological Phenotype of Cloned Mice
Somatic Cell Nuclear Transfer
Edited by: Peter SutovskyISBN: 0-387-37753-0
» Get more information about this book at landesbioscience.com «
Chapter authors:
Kellie L. K. Tamashiro, Randall R. Sakai, Yukiko Yamazaki, Teruhiko Wakayama and Ryuzo Yanagimachi
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Kellie L. K. Tamashiro
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine and Neuroscience Program, Department of Psychiatry, University of Cincinnati College of Medicine
Randall R. Sakai
Neuroscience Program, Department of Psychiatry, University of Cincinnati College of Medicine
Yukiko Yamazaki
Institute for Biogenesis Research, University of Hawaii School of Medicine
Teruhiko Wakayama
Institute for Biogenesis Research, University of Hawaii School of Medicine
Ryuzo Yanagimachi
Institute for Biogenesis Research, University of Hawaii School of Medicine
Additional chapters from this book:
Nuclear Remodeling and Nuclear Reprogramming for Making Transgenic Pigs by Nuclear Transfer
Randall S. Prather
A better understanding of the cellular and molecular events that occur when a nucleus is transferred to the cytoplasm of an oocyte will permit the development of improved procedures for performi...
Somatic Cell Nuclei in Cloning: Strangers Traveling in a Foreign Land
Keith E. Latham, Shaorong Gao and Zhiming Han
The recent successes in producing cloned offspring by somatic cell nuclear transfer are nothing short of remarkable. This process requires the somatic cell chromatin to substi- tute functionally ...
Cloning Cattle: The Methods in the Madness
Björn Oback and David N. Wells
Somatic cell nuclear transfer (SCNT) is much more widely and efficiently practiced in cattle than in any other species, making this arguably the most important mammal cloned to date. While the i...
Centrosome Inheritance after Fertilization and Nuclear Transfer in Mammals
Qing-Yuan Sun and Heide Schatten
Centrosomes, the main microtubule organizing centers in a cell, are nonmembrane-bound semi-conservative organelles consisting of numerous centrosome proteins that typi- cally surround a pair of p...
Developmental, Behavioral and Physiological Phenotype of Cloned Mice
Kellie L. K. Tamashiro, Randall R. Sakai, Yukiko Yamazaki, Teruhiko Wakayama and Ryuzo Yanagimachi
Cloning from adult somatic cells has been successful in at least ten species. Although generating viable cloned mammals from adult cells is technically feasible, prenatal and perinatal mortality...
Nucleolar Remodeling in Nuclear Transfer Embryos
Jozef Laurincik and Poul Maddox-Hyttel
Transcription of the ribosomal RNA (rRNA) genes occurs in the nucleolus and results in ribosome biogenesis. The rRNA gene activation and the associated nucleolus forma- tion may be used as a mark...
Somatic Cell Nuclear Transfer (SCNT) in Mammals: The Cytoplast and Its Reprogramming Activities
Josef Fulka, Jr. and Helena Fulka
It is now more than nine years since Dolly, the world’s first somatic cell cloned mammal was born, and the success of somatic cell nuclear transfer (SCNT) is still disappointingly low. Only abou...
Mitochondrial DNA Inheritance after SCNT
Stefan Hiendleder
Mitochondrial biogenesis and function is under dual genetic control and requires extensive interaction between biparentally inherited nuclear genes and maternally inherited mitochondrial genes. ...
Activation of Fertilized and Nuclear Transfer Eggs
Christopher Malcuit and Rafael A. Fissore
In all animal species, initiation of embryonic development occurs shortly after the joining together of the gametes from each of the sexes. The first of these steps, referred to as “egg activati...
