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Chapter category: Surgery

Perioperative Blood Transfusion in Hepatocellular Carcinomas

This chapter appears in the following book:

Recent Advances in Liver Surgery

Edited by: Renzo Dionigi
ISBN: TBA
» Get more information about this book at landesbioscience.com «

Chapter authors:
Gianlorenzo Dionigi, Salvatore Cuffari, Giovanni Cantone, Alessandro Bacuzzi and Renzo Dionigi


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Allogeneic blood transfusion during liver resection for malignancies has been associated with an increase incidence of different types of complications: infectious complications, tumor recurrence, decreased survival. Even if there is clear evidence of transfusion‑induced immunosuppression, it is difficult to demonstrate that transfusion is the only determinant factor that decisively affects the outcome. In any case there are several motivations to reduce the practice of blood transfusion. Advantage and drawbacks of different transfusion alternatives are reviewed, emphasizing that surgeons and anesthetists, who practice in Centers with high volume of liver resections, should be familiar with all the possible alternatives.

Gianlorenzo Dionigi
Department of Surgical Sciences, Azienda Ospedaliera-Polo Universitario, Via Guicciardini

Salvatore Cuffari

Giovanni Cantone

Alessandro Bacuzzi

Renzo Dionigi

» Access chapter for $19



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