Chapter category: Viruses
A Role for Chemokine Activity in Alphavirus Pathogenesis: Evidence from the Analysis of Polyarthritis and Myalgia Post Ross River Virus Infection
Chemokines in Viral Infections
Edited by: Surendran MahalingamISBN: 0-306-48234-7
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Chapter authors:
Brett A. Lidbury and Surendran Mahalingam
Ross River virus (RRV) is an \"Old World\" alphavirus of the Semliki Forest group1 and the etiological agent of the most common arthropodborne viral disease in Australia. RRV has a positive strand RNA genome comprising 11,851 nucleotides in a single strand organized into regions encoding nonstructural proteins (nsP 1-4) and four structural genes (capsid, E3, E2, 6K, E1). The genetic organization of RRV also includes a 5\' terminal cap and 3\' poly(A) tract1 resulting in the viral RNA acting in the host cell cytoplasm as a messenger RNA molecule. RRV is transmitted by both fresh and salt water mosquitoes.
Brett A. Lidbury
Surendran Mahalingam
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A Role for Chemokine Activity in Alphavirus Pathogenesis: Evidence from the Analysis of Polyarthritis and Myalgia Post Ross River Virus Infection
Brett A. Lidbury and Surendran Mahalingam
Ross River virus (RRV) is an \"Old World\" alphavirus of the Semliki Forest group1 and the etiological agent of the most common arthropodborne viral disease in Australia. RRV has a positive...
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