Ischemia-Reperfusion
Chapters
« previous | page 2 of 2 pagesThe Role of Superoxide in Heart Disease
James J. Galvez and R. Mark Payne
Is a common event in human pathophysiology. Ischemia occurs when blood flow has slowed, or stopped, and cannot meet the metabolic demands of the tissues. This happens, for example, in the event of stroke or heart attack. It also happens in the more predictable settings of surgery, such as coro...
Therapeutic Utilities of SOD Mimetics Cancer, Radiotherapy and SOD Mimetics
Daila S. Gridley, Lora M. Green, Gregory A. Nelson, Michael J. Pecaut and James M. Slater
Radiation is a major form of cancer therapy that has been successfully utilized for many decades. Over the years, substantial improvements have been made in radiotherapy regimens, resulting in increased survival time and improved quality of life. However, normal tissues in the vicinity of the ...
Therapeutic Utilities of SOD Mimetics Superoxide Dismutase and Parkinson’s Disease
Serge Przedborski and H. Ischiropoulos
Superoxide dismutase (SOD) is a group of enzymes, which is often regarded as the first line of cellular defense against the deleterious effects of reactive oxygen species (ROS). Oxidative stress that results from the production and reactivity of ROS has emerged as a main pathogenic event in hu...
Therapeutic Utilities of SOD Mimetics Cancer, Radiotherapy and Sod Mimetics
Daila S. Gridley, Lora M. Green, Gregory A. Nelson, Michael J. Pecaut and James M. Slater
Radiation is a major form of cancer therapy that has been successfully utilized for many decades. Over the years, substantial improvements have been made in radiotherapy regimens, resulting in increased survival time and improved quality of life. However, normal tissues in the vicinity of the tum...
Therapeutic Utilities of SOD Mimetics Superoxide Dismutase and Parkinson’s Disease
S. Przedborski and H. Ischiropoulos
Superoxide dismutase (SOD) is a group of enzymes, which is often regarded as the first line of cellular defense against the deleterious effects of reactive oxygen species (ROS). Oxidative stress that results from the production and reactivity of ROS has emerged as a main pathogenic event in human...
Therapeutic Utilities of SOD Mimetics: Catecholamines, Superoxide and Septic Shock
Heather Macarthur
Septic shock occurs when control is lost of the normal defense mechanisms of the body. This results in an inappropriate production of inflammatory mediators including free radicals. A major manifestation of septic shock is the development of a vascular crisis characterized by nonresponsiveness...
Therapeutic Utilities of SOD Mimetics: Oxidative Stress and Novel Antioxidants in the Treatment of AIDS-Related Brain Disorders
Vincenzo Mollace, Carolina Muscoli, Robert Nistico and Domenicatonio Rotiroti
Neurodegenerative disorders are frequently found in patients suffering from Acquired Immune Deficiency Syndrome (AIDS). Indeed, the occurrence of neuronal cell death, astrogliosis and mielodistrophy has commonly been described in patients undergoing HIV infection (60-80% at postmortem), unless...
Therapeutic Utilities of SOD Mimetics: Oxidative Stress and Novel Antioxidants in the Treatment of AIDS-Related Brain Disorders
Vincenzo Mollace, Carolina Muscoli, Robert Nistico and Domenicatonio Rotiroti
Neurodegenerative disorders are frequently found in patients suffering from Acquired Immune Deficiency Syndrome (AIDS). Indeed, the occurrence of neuronal cell death, astrogliosis and mielodistrophy has commonly been described in patients undergoing HIV infection (60-80% at postmortem), unless HI...
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